COVID vaccines target a relatively static spike protein. Since pancreatic tumors are genetically diverse, is the "personalized" approach for every patient scalable, or will it remain a boutique treatment for the wealthy?
Who knows?! I'm more optimistic for niche vaccines. Here in Argentina in some areas the farm workers can get https://en.wikipedia.org/wiki/Jun%C3%ADn_virus the symptoms are like Ebola, "you bleed and you die", but it's not transmisible from human to human, only from mice. There is now a vaccine that is applied only to people that leve in risk areas and have risky work.
There are plenty of niche illness like that, and I hope someone can make a production line for those vaccines (after passing ALL the safetly and effectivity test, obviously).