• matsemann 7 hours ago

    I love how Nobel Prize always have a "popular information" with nice layman description of what was discovered and why it was important. From the sidebar: https://www.nobelprize.org/prizes/medicine/2025/popular-info...

  • A_D_E_P_T 7 hours ago

    It's a win for nominative determinism. The name Shimon, in Japanese, directly translates to something like "Determined Scholar."

    It's also a fairly weird and old fashioned name. The sort of thing that would have been in style 120 years ago. (Meiji and early Taisho era.) Japanese names today are usually less literal.

    • coef2 3 hours ago

      His name could be interpreted as "aspiring to be a scholar". I guess he's done an exceptional job living up to it.

    • jelsisi 27 minutes ago

      Very excited to live in a timeline where autoimmune diseases could be cured. 40 people are already in remission from Lupus in a trial conducted last year.

      • slider22 6 hours ago

        In the past here on HN, someone spoke of a set of books that were an incredible resource on the body’s immune response. Does anyone know which books those were? I’m assuming they will get an update to include info on T-reg.

        • blackbear_ 5 hours ago

          As a general introduction I quite like this one: https://shop-us.kurzgesagt.org/products/immune-a-journey-int...

          • fabian2k 6 hours ago

            These discoveries are old enough to be in the textbooks already.

            Not sure what would be good popular science books. There is quite a lot on the immune system in the Alberts (Molecular Biology of the Cell), but that is maybe too much without solid biology background knowledge. The typical textbook is the Janeway (Immunology), but that's certainly too much.

            What I liked as an introductory textbook in general was Campbell Biology, but that covers essentially all of Biology. There is a chapter on the immune system as well.

            All those books are horribly expensive in the US, and still quite expensive in other countries, though.

            • jsenn 5 hours ago

              I don’t know the post you’re referring to but I highly recommend How the Immune System Works by Lauren Sompayrac. It explains the interesting parts without getting bogged down in the details of every signalling pathway, but without dumbing things down too much.

              • smath 5 hours ago

                “How the immune system works”, Lauren Sompayrac

              • haunter 6 hours ago

                Ah it's the Nobel Prize week! If anyone curious about this week's schedule:

                Tuesday: physics. Wednesday: chemistry. Thursday: literature. Friday: peace. Monday: economics.

                • Keyframe 6 hours ago

                  obligatory comment about how economics one isn't a Nobel prize.

                  • alkonaut 5 hours ago

                    Next Monday also isn’t in this week so it all works out.

                  • mongol 6 hours ago

                    The peace prize can't come soon enough. Trump is certainly going to throw a fit

                    • zenitsukz 5 hours ago

                      The best take I saw was giving it to USAID

                      • alkonaut 5 hours ago

                        Is it seven or eight wars he ended this term? I imagine if he could just remember at least two then he’d be a favorite for the prize.

                        • breadwinner 3 hours ago

                          He's starting wars in Portland, Los Angeles, and Chicago. Trump told the military last week, "This is going to be a major part for some of the people in this room. That's a war too. It's a war from within."

                          • falcor84 an hour ago

                            Was there ever a clear exception stating that you're ineligible for a Nobel in regards to stopping a war that you yourself started?

                            • stevenwoo 7 minutes ago

                              The Peace Prize has had quite a few weird choices, like Kissinger when that simply meant the USA would stop participating in the Vietnamese civil war (and to be generous putting a stop to USA bombing campaigns that Kissinger advocated in Vietnam and surrounding countries) or Barack Obama for giving a few speeches after less than a year in office. So it's not out of the question but it's hard to see the logic behind Trump getting one now.

                        • haunter 6 hours ago

                          Here are the current favorites accross the betting sites, I mean Trump has a decent chance

                          https://files.catbox.moe/xc1ik1.png

                          (NATO is a funny one too lol)

                          • ace32229 2 hours ago

                            Betting sites set their odds to maximise their revenue, not reality ;)

                            Polymarkets currently has him at 3%

                            https://polymarket.com/event/nobel-peace-prize-winner-2025?t...

                            • koakuma-chan 3 hours ago

                              files.catbox.moe has a security policy called HTTP Strict Transport Security (HSTS), which means that Firefox can only connect to it securely. You can’t add an exception to visit this site.

                              Why is Firefix blocking it? Is HSTS somehow bad?

                              Oh there's something with their certificate

                              • phrotoma 6 hours ago

                                holy fuck people will bet on pretty much anything I guess huh?

                                • andrewinardeer 5 hours ago

                                  I bet you they won't.

                                  • triceratops 3 hours ago

                                    I will take that bet. It's very easy for me to win.

                              • willvarfar 6 hours ago

                                Yes it is sad that the whole Nobel prize coverage will be just a background to a week talking about Trump, whether he wins or not :(

                                • giarc 3 hours ago

                                  He won't win. How could the committee look at him, while he is actively celebrating killing people off the coast of Venezuela (whether they are smuggling drugs or not) and give him the Peace Prize.

                                  • criddell 2 hours ago

                                    I guess it depends on whether or not the committee members plan on visiting the US anytime soon.

                                    • tdeck 2 hours ago

                                      Trump isn't good enough at blackmail. Netanyahu, on the other hand...

                                    • slightwinder 5 hours ago

                                      I don't think anyone seriously believes he will win. Despite making up all kind of wars and conflicts he claims to have solved, there hasn't been any real peace coming from him, yet. Maybe Gaza turns out to something real, but it's not done yet, and I kinda doubt they decide on these prices on a short whim. And if development in the USA continues like at the moment, I doubt he will be considered next year. It will be just one conflict cancelling out one peace.

                                      • jeffbee 3 hours ago

                                        > anyone seriously believes

                                        The brain donors at NPR Morning Edition, the mission of which is to remind me daily to never donate to NPR, spent some airtime this morning discussing Gaza peace talks and how they are motivated by and leading to a Trump Nobel.

                                        • garbthetill 5 hours ago

                                          but what if he turns into the ultimate humanitarian after he wins one? Has the nobel committee considered that?/s

                                          Yeah its weird how he explicitly states he wants a peace prize and then turns around and does very hellish things, rips up Aid programs, impose one sided tariffs without caring about your allies, belittle a president desperately trying to fight for his countries sovereignty, mafia style negotiations for said country minerals without a security guarantee in order to send weapons, trash nato allies repeatedly, taunt allies that you wont honor security guarantees if they dont do x , remove historical names for no good reason from various government objects , alienate out entire class of people with your rhetoric while using a platform thats supposed to be bipartisan, deport & arrest people while bypassing judges as much as you can

                                          • BolexNOLA 5 hours ago

                                            >but what if he turns into the ultimate humanitarian after he wins one? Has the nobel committee considered that?/s

                                            Ugh giving me flashbacks to the “the office will change him” arguments. Can’t believe people actually said that out loud.

                                            If he somehow got the peace prize as he balloons a department sneaking around in plain clothes with their faces covered rounding people up at work and terrifying/ripping families apart then the prize is truly a joke. Luckily there’s no way he’s getting it.

                                        • matsemann 5 hours ago

                                          Oh well, the comments will also be filled with complaints about Kissinger, Obama, Teresa, Arafat... and how the prize therefore somehow is worthless. 2020 thread has 30 comments mentioning Trump, 20 comments mentioning Obama.. https://news.ycombinator.com/item?id=24728142

                                          Instead of celebrating the winners, some people just want to complain.

                                          • IAmBroom 4 hours ago

                                            Both are valid topics.

                                            • matsemann 4 hours ago

                                              Sure, but is it worth discussing again and again and again? To me it's like beating a dead horse. Every year, the same discussion here. Drowns the more interesting discussion about the actual winners.

                                              • busyant 3 hours ago

                                                I get your point.

                                                It is possible, however, that it's different people each year having roughly the same conversation.

                                                But this is true of many topics.

                                            • boxed 5 hours ago

                                              > Instead of celebrating the winners

                                              Well.. assuming the winner isn't a war criminal we can celebrate at least :P

                                      • marcelotournier 2 hours ago

                                        First pattern that comes into mind after reading about a gene called "Foxp3" and immune targets:

                                        Man frantically shakes whole body, then raises dramatically his fist and screams: - FOX...