• ZeroGravitas 3 days ago

    This bit feels like it should have been given more detail:

    > In his written testimony, Jørgensen said Novo Nordisk’s insulin product Levemir was previously available to 90% of U.S. patients through formularies. But insurers began to drop coverage of the insulin after Novo Nordisk cut its list price, leading to only 36% of patients having access.

    > That eventually drove the company to discontinue the insulin

    So insurers are refusing to buy cheaper drugs? What's the story there?

    • Laksen 3 days ago

      It's the American PBMs that make their money on the difference between the list price and the price they sell it for. Higher list price means more profit

      This was repeated over and over in the hearing. And apparently the regulation of PBMs (changed about a year ago) hasn't resulted in PBMs taking up cheaper drugs

      • ZeroGravitas 3 days ago

        An interesting article on this found thanks to your help with search keywords:

        https://www.americanprogress.org/article/5-things-to-know-ab...

        • emchammer 2 days ago

          This article is almost unbelievable. This whole thing seems like an incredibly complex racket comparable to cryptocurrency securities fraud.

        • salawat 2 days ago

          You mean the difference between wholesale price of the manufacturer and the negotiated discount by the PBM right? Your use of pronouns obfuscates who you're talking about.

        • ywvcbk 3 days ago

          Do American insurance companies have any incentives to minimize their spending?

          • Ekaros 2 days ago

            As in not paying out money yes. As in keeping costs low no...

            • s1artibartfast a day ago

              Thats not correct. It is actually the exact opposite.

              The ACA places profit controls on for insurance companies how much they can make as a percent of what they pay out (aka the 80/20 rule).

              They must pay out 80% in coverage with profit and operation expenses coming from the other 20%.

              Therefore, the best way to increase profit is to ensure the total price of healthcare they cover goes as high as possible. It is better to make 20% of a $1,000 drug than a $10 one.

              • tiahura 2 days ago

                A $ is a $.

                • willcipriano 2 days ago

                  20% of 2 dollars is better than 20% of 1 dollar.

            • Bluescreenbuddy a day ago

              If a drug has low profitability, this is what happens. It's harming low cost but critical drugs

            • anonzzzies 3 days ago

              But don't all other companies do the same? Also ones in the US itself? So far any price on any prescription drug I have seen on reddit by US people and companies is far cheaper here. For instance; omeprazole prescription seems to be $90 and otc $32 for almost a month: I pay less than 3 euros here (got them yesterday). Not sure who is doing it, but every US price I have seen is at least 10x higher than it is here in the EU.

              • casualscience 3 days ago

                The story goes that the US subsidizes all the drug prices around the world. Without the insane US margins, drug companies wouldn't ever do the needed R&D... so they say.

                • ZeroGravitas 3 days ago

                  If the free market has decided it's more efficient to let Americans suffer horribly and then die, who are we to argue.

                  • iwontberude 2 days ago

                    Americans like suffering, stop trying to take this from them.

                  • gklitz 2 days ago

                    The “insane US margins” don’t go to the pharma companies, they go to the PBM middlemen who take home the majority of the list price, and therefore have interest in higher list prices, which also increases copay. That’s why it’s consistent across the USA market, and why they drop products that lower prices.

                    • wernerb 3 days ago

                      Wasn't if part of US law that medicine prices cannot be negotiated?

                      • jackTheBuilder 3 days ago

                        Medicare + Medicaid has been prohibited from assisting negotiation of drug price between pharmacy + drug company for a few decades. That is set to change in the future id my understanding.

                        I have private health care insurance so my insurance company would try negotiate the price down.

                        I agree with other commenters saying basically, drug companies all around the world do R&D, are happy to sell drugs at cost in England or Somalia, but will aim to make money in US selling drugs with a healthy profit margin here.

                        • JumpCrisscross 2 days ago

                          > Medicare + Medicaid has been prohibited from assisting negotiation of drug price between pharmacy + drug company for a few decades. That is set to change in the future id my understanding

                          It’s already started [1].

                          [1] https://www.cnn.com/2023/08/29/politics/medicare-drug-price-...

                          • howard941 2 days ago

                            Slowstarted

                          • ywvcbk 3 days ago

                            > so my insurance company would try negotiate the price down.

                            Do they have any incentives to do that though? If their profits are fixed at a specific % wouldn’t they be incentivized to spend as much as possible so that they could increase premiums (as long as all other companies play along)?

                            • 1123581321 3 days ago

                              If premiums are too high, employers will switch the insurance company they offer employees.

                              • triceratops 3 days ago

                                To whom? Everyone will do the same because everyone's incentives are the same.

                                • 1123581321 2 days ago

                                  You’re talking about something theoretical. I’m telling you what actually happens.

                                  Insurance companies lose business when their premiums are unnecessarily high. In the long run, all their prices go up, but those who manage rising costs better (and provide better service and all that other stuff), grow their businesses.

                                  • triceratops 2 days ago

                                    I think you're being theoretical. Insurers can only increase profits by inflating medical costs.

                                    "Insurers are supposed to spend 80% of every dollar on care and only 20% on administrative costs. However, instead of lowering premiums, the insurance companies have been incentivized to increase costs so that they can make more money."

                                    https://penncapital-star.com/uncategorized/americans-suffer-...

                                    • 1123581321 2 days ago

                                      I am not sure what else to tell you. Companies switch insurance providers for cost all the time. I've benefitted from it several times and seen first-hand how competitive the selection/sales process can be. If an insurer thought they could coast on high prices, losing accounts would change their behavior quickly, like in any company.

                                      As an industry, insurers all benefit from aggregate rising medical costs because of the percentage rule you mentioned, but that's not the same as what an individual insurer will do.

                                      If you're arguing as a proxy for wanting public health to be allowed to enter the industry as a price negotiator, I'm in complete agreement.

                                      • nradov 2 days ago

                                        There's nothing theoretical about price competition. Large self-insured employers and other group buyers are very price sensitive. If a company offered Aetna health plans to their employees this year they would happily switch to Humana next year to save a few dollars. There are sophisticated analytics tools available now which let those customers predict future costs under various options.

                                    • JumpCrisscross 2 days ago

                                      > To whom?

                                      Themselves. Plenty of companies hold the risk and outsource administration.

                                • ZeroGravitas 3 days ago

                                  In the article the drug maker suggestss that rather than negotiate the price down, US insurers stop buying the drug if he cuts the price too low.

                                  That seems like a wild claim to make, but since it's just reported as if that was normal rather than a shocking scandal, I guess it's probably true.

                                  • whaleofatw2022 3 days ago

                                    It's part of the grift. Expensive drugs means all sorts of middle men negotiate concessions to make themselves get better performance reviews.

                              • pasabagi 2 days ago

                                I've read that big pharma are primarily patent companies: most of the actual research is done by universities, then most of the production is outsourced.

                                • s1artibartfast a day ago

                                  That simply isnt true and is a political fiction.

                                  Pharma companies spend 10x what universities and the NIH do.

                                  The only grain of truth in it is if you compare a tiny subset of what pharma companies do, and look only are extremely early drug exploration, and ignore all of the subsequent development like drug screening, testing, formulation, and clinical trials.

                              • faangguyindia 3 days ago

                                U can get it dirt cheap from India (indian pharma grade from sunpharma)

                              • pjfin123 2 days ago

                                > In a release, the Senate Health Committee said it would cost the U.S. $411 billion per year if half of all Americans took weight loss drugs from Novo Nordisk and Eli Lilly. That’s $5 billion more than what Americans spent on all prescription drugs in 2022.

                                If these drugs are effective as they seem to be they might still be worth it at this price. Giving most Americans Ozempic would probably improve people's health more per $ than the current medical system is.

                              • JumpCrisscross 2 days ago

                                There are three problems: the capital cost of scaling production, PBMs and the absurd margins Novo Nordisk is milking.

                                PBMs are a separate issue. But the grand bargain in the first and last is the U.S. giving Novo Nordisk a loan in exchange for domestic production and a fixed price for the term of the loan, e.g. $50 per month, $9 cheaper than what they charge in Germany [1].

                                [1] https://www.help.senate.gov/chair/newsroom/press/prepared-re...

                                • 1GZ0 3 days ago

                                  Maybe the reason that drug prices in the US are higher across the board has more to do with insurers than the drugmakers? Sure seems like it.

                                  • gklitz 2 days ago

                                    Lost all respect for Bernie on this. He’s just blatantly saying that he’s colluding with PBMs. And imagine the absurdity of what he’s saying at the trial.

                                    He’s saying he’s had pre talks with PBMs and they are going “we are actually willing to accept lower prices, we promise not to stop buying if you lower prices” Why would you even be in this situation in a normal market? The willingness to accept lower prices on a product should be automatic and the threat of not buying should be driving prices down not up. If the market was sane, the PBMs would be going: “Lower prices or we stop buying”

                                    But the scam is, PBMs are eating up 70%+ of the “list price” Americans aren’t buying drugs from Pharma companies, they are buying them from their Insurance/PBM/Pharmacy collusion, who dictate both which products you are allowed to buy under insurance and what the “pretend” list price is, so they push it up to maximize their own profits and maximize your copay, which is calculated based on a hypothetical list price they have inflated 4x times while in reality only paying 25% of it themselves.

                                    • datavirtue 3 days ago

                                      Jørgensen pointed out how drugs were only 10% of medical costs and that the real issue was obesity and the many diseases that accompany it making the drugs required in the first place.

                                      No one seemed interested in the truth.

                                      • AStonesThrow 2 days ago

                                        Most of the drugs that I've been offered have weight-gain as a prominent and common side effect. Some parents even got irate about gynecomastia, which is typically not seen isolated from obesity.

                                        How many drugs on the market have "loss of appetite/weight" as a side effect? Probably none, outside of the ones currently labeled for it. And methamphetamine. Well, there was also AZT, Fen-Phen... Didn't heroin help a few folks slim down a bit?

                                        https://en.wikipedia.org/wiki/Heroin_chic

                                        • DangitBobby 2 days ago

                                          I'm not obese and still have a prescription. Same with my wife, except she has 3. What now?

                                          • ImJamal 2 days ago

                                            Your wife has 3 prescriptions for Ozempic? We aren't talking about random prescriptions here...

                                          • ImJamal 2 days ago

                                            It is easier to take a drug than to eat better and work out.

                                          • undefined 3 days ago
                                            [deleted]
                                            • potatoicecoffee 3 days ago

                                              maybe the american government should start negotiating drug prices more effetively like the australia does with the pharmaceutical benefits scheme

                                              • InfiniteLoup 3 days ago

                                                'Start paying us off like the US pharmaceutical companies do': Senate grills Novo Nordisk CEO on Ozempic drug pricing /s

                                                • vpastore 2 days ago

                                                  [dead]

                                                  • floppiplopp 3 days ago

                                                    Oh, oh! Now do US pharma companies... and and, landlords. Yeah, that'll be great. And then private equity. Those are just plain bastards. Is this the end of free market capitalism?